Following a court appearance for drunk driving, Leo is required to perform unpaid work as a punishment, assisting AJ, a community worker on a run-down,largely black-occupied housing estate in South London. AJ is hoping to divert boys away from crime by encouraging them to do sports, and, though initially dismissive of Leo as a white intruder, comes to respect him after he has saved the life of Errol, a former gang member now anxious to keep his little brother Levi out of trouble. Errol has been stabbed in the leg by members of a gang from a rival estate and Leo stops him from bleeding to death. Earlier in the week a young girl called Shana Block was stabbed to death at a funfair and her murder recorded on a mobile phone. As Shana lived on the estate police sergeant Wallace involves Leo as a go-between with the suspicious residents. Also on the scene are Harry and Nikki, the latter dating Ryan, a young Scottish paramedic she met when called to the scene of Shana's death.

　　The pathologists investigate when a military helicopter crashes into a refugee detention center. Harry and Nikki actually witnessed the crash and were first on the scene but the case is complex since the center was Ministry of Defense property leased to the Home Office. The team is shocked at the conditions they find in the center and Harry, who has a close friend in the RAF, is shaken when a government Minister attributes the accident to pilot error.

　　When a boat carrying illegal passengers is found crashed in the Thames, the team investigate.

　　The team is shocked when Leo Dalton's wife and daughter are killed when a fancy sports car careens out of control and smashes into a café. The police are puzzled by the cause of the crash but believe the driver may have been involved in a identity theft ring when they find several several passports and ID cards in the vehicle. Meanwhile, Nikki must perform urgent autopsies on two bodies found floating in the river.

　　A Time to Heal -The team is called out to Northern Ireland to investigate the bodies of two men killed by paramilitaries twenty years ago. For Sam, it is a case that is soon to turn personal…
　　Death by Water - Tensions are running high in the ‘leaderless’ team as Leo and Harry clash over an investigation into an outbreak of breathing difficulties among children on the South Coast.
　　Nowhere Fast - When members of a race horse owning syndicate are killed in a helicopter crash, Leo and Harry investigate – and an unexpected new face at the mortuary lends a helping hand.
　　Body 21 - Approached by a group of survivors from a recent train crash, the team investigate the wreckage and a new mystery – the identity of the unidentified body 21.

　　本劇改編自豆瓣閱讀連載小說(shuō)《一生懸命》，作者、編劇陸春吾。
　　倪向東（尹昉 飾）收到好友曹小軍（白宇帆 飾）的請(qǐng)求，將一只木箱運(yùn)送到荒山上的廢棄小屋，卻意外發(fā)現(xiàn)箱里裝的竟是曹小軍的尸體。曹小軍的妻子吳細(xì)妹（李庚希 飾）報(bào)警尋找失蹤的丈夫，并暗指一切都和倪向東有關(guān)?？勺鳛樽C人，吳細(xì)妹的供詞前后矛盾，且夫妻二人的孩子并非曹小軍親生。在警方的連環(huán)追問(wèn)下，吳細(xì)妹迫不得已講述了三人的往事。
　　三人曾是好友，吳細(xì)妹與倪向東是一對(duì)戀人，倪向東不愿為孩子負(fù)責(zé)，曹小軍挺身而出帶她遠(yuǎn)走高飛，一起撫養(yǎng)孩子。在追查過(guò)程中，警方進(jìn)一步發(fā)現(xiàn)吳細(xì)妹的孩子和倪向東也沒(méi)有血緣關(guān)系，大家對(duì)倪向東的評(píng)價(jià)還存在完全不同的兩種聲音：老家的人說(shuō)倪向東無(wú)惡不作；工友卻說(shuō)他與人為善，還資助了一位姓徐的老人。
　　老警員孟朝（張哲華 飾）帶著新人童浩（徐奧俊 飾），從北方海岸到南方密林，抽絲剝繭，揭開(kāi)了吳細(xì)妹、曹小軍、倪向東糾纏了十余年的連環(huán)殺局，讓作惡之人得到了法律的制裁。

　　這是一部展示我國(guó)緝毒警察智勇雙全，與販毒犯罪分子展開(kāi)殊死斗爭(zhēng)的故事。
　　某市一連串發(fā)生命案，經(jīng)調(diào)查這都與涉毒有關(guān)，為此，公安局張局長(zhǎng)指示刑警隊(duì)隊(duì)長(zhǎng)雷霆成立專(zhuān)案小組偵破這些系列販毒案，派出所治安警沙城也加入刑警隊(duì)專(zhuān)案小組。在辦案過(guò)程中，隊(duì)長(zhǎng)雷霆等干警發(fā)現(xiàn)新型毒品已經(jīng)開(kāi)始滲入某市。為了打擊制毒犯罪團(tuán)伙，追查制毒配方的來(lái)源，公安局領(lǐng)導(dǎo)安排年輕的女刑警張葉和沙城一起到大學(xué)化學(xué)樓展開(kāi)調(diào)查，張葉和沙城在調(diào)查中發(fā)現(xiàn)科技精英宮教授竟然是罪惡的幫兇。為了引出毒梟昆哥，雷霆派張葉只身進(jìn)入敵穴展開(kāi)智與勇的較量，終于在兩代警員的共同努力下，破獲了一個(gè)利用娛樂(lè)城販毒的犯罪團(tuán)伙。

　　經(jīng)過(guò)千挑萬(wàn)選，沃威（萬(wàn)思維 飾）、姜竇（蒲巴甲 飾）等一批有志青年被選到陸航大隊(duì)，在教官鄭北（王強(qiáng) 飾）帶領(lǐng)下，組成了一個(gè)全能型飛行特訓(xùn)班。學(xué)員們出身不同、秉性各異，組建之初就略見(jiàn)分曉。在嚴(yán)格的訓(xùn)練中，以鄭北為首的教官隊(duì)伍針對(duì)學(xué)員特質(zhì)，制定了非常規(guī)教學(xué)手段，為培養(yǎng)新時(shí)期后備人才做了探索性試驗(yàn)。急流勇進(jìn)、大浪淘沙，學(xué)員們?cè)谟?xùn)練中顛覆自我，展現(xiàn)了一幅幅狹路相逢、絕處逢生的青春畫(huà)面。有的人自感得意時(shí)遭淘汰，也有的遇坎坷自我迷失，更有甚者陷入情感糾葛。在不斷斗智斗勇中，學(xué)員與教官、上級(jí)與下級(jí)、男學(xué)員與女教官，上演著環(huán)環(huán)相扣的明暗斗法。最終使大家理解了什么是“戰(zhàn)友”......

　　本劇講述了四個(gè)美麗睿智的女孩何茹、林依蘭、小辣椒和安子背井離鄉(xiāng)到南濱打工的故事。她們雖然同時(shí)漂泊在海濱，但對(duì)生活的態(tài)度及命運(yùn)卻截然不同，她們經(jīng)歷著欲罷不能的戀情；經(jīng)歷著一同歡笑一同流淚而又矛盾重重的友情；經(jīng)歷著對(duì)未知?dú)w宿的迷茫和生離死別的變遷……

　　根據(jù)真實(shí)案件改編，創(chuàng)建國(guó)以來(lái)涉案金額之最，涉雜官員之廣為中國(guó)審計(jì)第一大案。
　　拍賣(mài)行行長(zhǎng)畏自殺，知情者接連神秘失蹤，幕后黑手輾轉(zhuǎn)數(shù)省瘋狂洗錢(qián)。警方出動(dòng)欲擒故縱，萬(wàn)惡之地緊急圍捕，無(wú)形巨網(wǎng)層層纏繞，牽一發(fā)，萬(wàn)劫不復(fù)。
　　前年前夕，以邵建川為領(lǐng)導(dǎo)的營(yíng)州市公安局經(jīng)濟(jì)偵察支隊(duì)接到一份國(guó)家審計(jì)總署駐營(yíng)州市特派員辦事處送來(lái)《關(guān)于營(yíng)州市華新銀行大量違軌出具金融票據(jù)和支行第三產(chǎn)業(yè)銀信拍買(mǎi)行的亂帳問(wèn)題的移送處理書(shū)》。營(yíng)州市公安局經(jīng)偵支隊(duì)立即針對(duì)此案成立了專(zhuān)寧組，對(duì)這起涉案金額巨大、震驚國(guó)家審計(jì)署的金融大案展開(kāi)了調(diào)查……
　　正在專(zhuān)案組開(kāi)始對(duì)營(yíng)州華新銀行行長(zhǎng)雷學(xué)文進(jìn)行問(wèn)訊之時(shí)，其下屬的銀信拍賣(mài)行會(huì)計(jì)倉(cāng)庫(kù)突然燃起大火，大量涉案票據(jù)付之一炬，而拍賣(mài)行副總經(jīng)理、雷學(xué)文的愛(ài)徒、營(yíng)州市著名女企業(yè)家齊曉梅的弟弟齊曉康，也在火災(zāi)中“不幸身亡”；隨后，拍賣(mài)行行長(zhǎng)黃有恒也在司法問(wèn)訊中不堪重負(fù)，墜樓自殺……在經(jīng)偵支隊(duì)隊(duì)長(zhǎng)、專(zhuān)案組組長(zhǎng)邵建川的帶領(lǐng)下，從開(kāi)發(fā)區(qū)一塊500畝的土地的買(mǎi)賣(mài)、機(jī)電暨建材商場(chǎng)的停工，古城旅游開(kāi)發(fā)項(xiàng)目被騙等紅索入手，終于找出了真正的幕后黑手營(yíng)州市華新銀行行長(zhǎng)雷學(xué)文。就在專(zhuān)案組即將實(shí)施抓捕的時(shí)候，雷學(xué)文卻在他的情人和崇拜者營(yíng)州華夏證券公司大忘掉室經(jīng)理何源的幫助下金蟬脫殼……帶著他的齊曉康、談君、曹衛(wèi)平等人，開(kāi)始了輾轉(zhuǎn)數(shù)省的瘋狂洗錢(qián)行動(dòng)。憑借對(duì)金融業(yè)務(wù)的精通及其手下的心狠手辣雷學(xué)文一次次逃脫了經(jīng)偵支隊(duì)的追捕，但他卻沒(méi)有料到這正是警方欲擒故縱的戰(zhàn)略……
　　就在雷學(xué)文自認(rèn)為已經(jīng)將大部分贓款洗進(jìn)自己兜里，準(zhǔn)備改換身份混入市政府經(jīng)濟(jì)委員會(huì)出國(guó)考察團(tuán)、偷渡出國(guó)的時(shí)候，魔高一尺、道高一丈，專(zhuān)案組當(dāng)機(jī)立斷地?cái)財(cái)嗔怂嘈慕?jīng)營(yíng)的非法途徑，立即實(shí)施圍捕……